BackgroundSkin-derived advanced glycation end products (sAGEs) have been associated with cardiovascular (CV) Onesie risk and mortality in adults.We hypothesize that cardiorespiratory fitness (CRF), body mass index (BMI) and vascular health are associated with development of sAGEs during childhood.MethodsIn our prospective cohort study, 1171 childre
Long-term memory retrieval bypasses working memory
For decades, it has been assumed that when humans retrieve information from long-term memory (LTM), information need first to be brought back BORAGE OIL into working memory (WM).However, as WM capacity is limited, it is unclear what happens if information from LTM needs to be retrieved while WM is fully engaged? To address this question, observers
The level of corporate social responsibility in Mexican franchises
This research evaluates the level of corporate social responsibility activities by the application of 26 indicators grouped according to the following dimensions: environment, society, corporate management and products and services.Beginning with the analysis 1139 of 401 websites of franchises that are currently operating in Mexico, 22.9% really co
The hyperinflammatory spectrum: from defects in cytotoxicity to cytokine control
Cytotoxic lymphocytes kill target cells through polarized release of the content of cytotoxic granules towards the target cell.The importance of this cytotoxic pathway in immune regulation is evidenced by the severe and often fatal condition, known as hemophagocytic lymphohistiocytosis (HLH) that occurs in mice and humans with inborn errors of lymp
The hyperinflammatory spectrum: from defects in cytotoxicity to cytokine control
Cytotoxic lymphocytes kill target cells through polarized release of the content of cytotoxic granules towards the target cell.The importance of this cytotoxic pathway in immune regulation is evidenced by the severe and often fatal condition, known as hemophagocytic lymphohistiocytosis (HLH) that occurs in mice and humans with inborn errors of lymp